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First of all one thing that I think is of utmost importance for you to know is that if you are a member of Balance Rewards and you use your reward card when picking up your prescription it will automatically give you 100 points for each one filled. In addition to a Balance Rewards card (which can be used at both Walgreens or Duane Reade), you can use any reward credit card, to earn some additional type of reward for your purchase. Discover is straightforward with its rewards and offers up to 5% back in rewards no matter what you purchase. Look for a reward card that has at least a 1.5% reward rate, unlimited potential for earning with points or miles that don’t expire and no annual fee.